Chiral spirocyclic phosphoric acid-catalyzed enantioselective synthesis of heterotriarylmethanes bearing an amino acid moiety

We present herein an enantioselective protocol for the chiral phosphoric acid-catalyzed addition of 3-arylisoxazol-5-amines to highly reactive 3-methide-3H-pyrroles to provide a diverse range of heterotriarylmethanes bearing an amino acid moiety in good yields (up to 97%) and high enantioselectiviti...

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Detalles Bibliográficos
Autores principales: Jiaping, Jin, Woldegiorgis, Alemayehu Gashaw, Lin, Xufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285616/
https://www.ncbi.nlm.nih.gov/pubmed/37362600
http://dx.doi.org/10.1039/d3ra03480a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285616/
https://www.ncbi.nlm.nih.gov/pubmed/37362600
http://dx.doi.org/10.1039/d3ra03480a

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