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Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target

We examined the effects of ∼30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone samples from four separate missions (BION-M1, rodent research [RR]1, RR9, and RR18). Spaceflight reduced GSK3β content across all missions,...

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Detalles Bibliográficos
Autores principales: Baranowski, Ryan W., Braun, Jessica L., Hockey, Briana L., Yumol, Jenalyn L., Geromella, Mia S., Watson, Colton J.F., Kurgan, Nigel, Messner, Holt N., Whitley, Kennedy C., MacNeil, Adam J., Gauquelin-Koch, Guillemette, Bertile, Fabrice, Gittings, William, Vandenboom, Rene, Ward, Wendy E., Fajardo, Val A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285634/
https://www.ncbi.nlm.nih.gov/pubmed/37360691
http://dx.doi.org/10.1016/j.isci.2023.107047