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Toward countering muscle and bone loss with spaceflight: GSK3 as a potential target
We examined the effects of ∼30 days of spaceflight on glycogen synthase kinase 3 (GSK3) content and inhibitory serine phosphorylation in murine muscle and bone samples from four separate missions (BION-M1, rodent research [RR]1, RR9, and RR18). Spaceflight reduced GSK3β content across all missions,...
Autores principales: | Baranowski, Ryan W., Braun, Jessica L., Hockey, Briana L., Yumol, Jenalyn L., Geromella, Mia S., Watson, Colton J.F., Kurgan, Nigel, Messner, Holt N., Whitley, Kennedy C., MacNeil, Adam J., Gauquelin-Koch, Guillemette, Bertile, Fabrice, Gittings, William, Vandenboom, Rene, Ward, Wendy E., Fajardo, Val A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285634/ https://www.ncbi.nlm.nih.gov/pubmed/37360691 http://dx.doi.org/10.1016/j.isci.2023.107047 |
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