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Activating FcγR function depends on endosomal-signaling platforms

Cell surface receptor internalization can either terminate signaling or activate alternative endosomal signaling pathways. We investigated here whether endosomal signaling is involved in the function of the human receptors for Fc immunoglobulin fragments (FcRs): FcαRI, FcγRIIA, and FcγRI. All these...

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Detalles Bibliográficos
Autores principales: Benadda, Samira, Nugue, Mathilde, Koumantou, Despoina, Bens, Marcelle, De Luca, Mariacristina, Pellé, Olivier, Monteiro, Renato C., Evnouchidou, Irini, Saveanu, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285637/
https://www.ncbi.nlm.nih.gov/pubmed/37360697
http://dx.doi.org/10.1016/j.isci.2023.107055