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Effects of hydroxyl group in cyclo(Pro-Tyr)-like cyclic dipeptides on their anti-QS activity and self-assembly

We investigated the influence of hydroxyl groups on the anti-quorum-sensing (anti-QS) and anti-biofilm activity of structurally similar cyclic dipeptides, namely cyclo(L-Pro-L-Tyr), cyclo(L-Hyp-L-Tyr), and cyclo(L-Pro-L-Phe), against Pseudomonas aeruginosa PAO1. Cyclo(L-Pro-L-Phe), lacking hydroxyl...

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Detalles Bibliográficos
Autores principales: Li, Li, Xu, Zuxian, Cao, Ruipin, Li, Jiaxin, Wu, Chang-Jer, Wang, Yinglu, Zhu, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285644/
https://www.ncbi.nlm.nih.gov/pubmed/37360689
http://dx.doi.org/10.1016/j.isci.2023.107048