Integration of NMR Spectroscopy in an Analytical Workflow to Evaluate the Effects of Oxidative Stress on Abituzumab: Beyond the Fingerprint of mAbs

[Image: see text] The assessment of the higher-order structure (HOS) by NMR is a powerful methodology to characterize the structural features of biologics. Forced oxidative stress studies are used to investigate the stability profile, to develop pharmaceutical formulations and analytical methods. He...

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Detalles Bibliográficos
Autores principales: Cerofolini, Linda, Ravera, Enrico, Fischer, Christian, Trovato, Andrea, Sacco, Francesca, Palinsky, Wolf, Angiuoni, Gabriella, Fragai, Marco, Baroni, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285717/
https://www.ncbi.nlm.nih.gov/pubmed/37278511
http://dx.doi.org/10.1021/acs.analchem.3c00317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285717/
https://www.ncbi.nlm.nih.gov/pubmed/37278511
http://dx.doi.org/10.1021/acs.analchem.3c00317

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