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KSHV infection drives poorly cytotoxic CD56-negative natural killer cell differentiation in vivo upon KSHV/EBV dual infection

Herpesvirus infections shape the human natural killer (NK) cell compartment. While Epstein-Barr virus (EBV) expands immature NKG2A(+) NK cells, human cytomegalovirus (CMV) drives accumulation of adaptive NKG2C(+) NK cells. Kaposi sarcoma-associated herpesvirus (KSHV) is a close relative of EBV, and...

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Detalles Bibliográficos
Autores principales: Caduff, Nicole, McHugh, Donal, Rieble, Lisa, Forconi, Catherine S., Ong’echa, John M., Oluoch, Peter O., Raykova, Ana, Murer, Anita, Böni, Michelle, Zuppiger, Lara, Schulz, Thomas F., Blackbourn, David J., Chijioke, Obinna, Moormann, Ann M., Münz, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10285879/
https://www.ncbi.nlm.nih.gov/pubmed/33951431
http://dx.doi.org/10.1016/j.celrep.2021.109056