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Identification of Potent hDHODH Inhibitors for Lung Cancer via Virtual Screening of a Rationally Designed Small Combinatorial Library

[Image: see text] Cancer is characterized by altered cellular metabolism, and metabolic enzymes are considered as a promising target for anticancer therapy. Pyrimidine metabolism dysregulation is associated with various types of cancer, particularly lung cancer, which is one of the leading causes of...

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Detalles Bibliográficos
Autores principales: Nada, Hossam, Kim, Sungdo, Park, Suin, Lee, Moo Yeol, Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286098/
https://www.ncbi.nlm.nih.gov/pubmed/37360481
http://dx.doi.org/10.1021/acsomega.3c01323