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Swim in the Chiral Pool: MDMA and MDA Enantiomers from Alanine-Derived Precursors

[Image: see text] A divergent two-step process has provided access to optically pure enantiomers of MDMA and MDA, clinically relevant phenylisopropylamine entactogens. Target compounds were synthesized from commercially available alanine-derived aziridines. Critical process parameters were identifie...

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Detalles Bibliográficos
Autores principales: Sherwood, Alexander M., Burkhartzmeyer, Elise K., Williamson, Samuel E., Faley, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286248/
https://www.ncbi.nlm.nih.gov/pubmed/37360440
http://dx.doi.org/10.1021/acsomega.3c02358