Using a Graph Convolutional Neural Network Model to Identify Bile Salt Export Pump Inhibitors

[Image: see text] The bile salt export pump (BSEP) is a key transporter involved in the efflux of bile salts from hepatocytes to bile canaliculi. Inhibition of BSEP leads to the accumulation of bile salts within the hepatocytes, leading to possible cholestasis and drug-induced liver injury. Screenin...

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Detalles Bibliográficos
Autores principales: AbdulHameed, Mohamed Diwan M., Liu, Ruifeng, Wallqvist, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286257/
https://www.ncbi.nlm.nih.gov/pubmed/37360478
http://dx.doi.org/10.1021/acsomega.3c01583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286257/
https://www.ncbi.nlm.nih.gov/pubmed/37360478
http://dx.doi.org/10.1021/acsomega.3c01583

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