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Design, Synthesis, and Biological Activity of Donepezil: Aromatic Amine Hybrids as Anti-Alzheimerss Drugs

[Image: see text] In this study, benzylpiperidine, the active group of donepezil (DNP), was connected with the neurotransmitter phenylethylamine by square amide, in which the fat chain of phenylethylamine was reduced and the benzene rings were substituted. A series of multifunctional hybrid compound...

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Detalles Bibliográficos
Autores principales: Wan, Dan, Wang, Feng-Qin, Xie, Jiang, Chen, Lin, Zhou, Xian-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286275/
https://www.ncbi.nlm.nih.gov/pubmed/37360465
http://dx.doi.org/10.1021/acsomega.3c01427