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A Leader-Guided Substrate Tolerant RiPP Brominase Allows Suzuki–Miyaura Cross-Coupling Reactions for Peptides and Proteins

[Image: see text] Bioorthogonal derivatization of peptides and proteins enables investigations into their biological function and allows for exploitation of their therapeutic potential, among other varied deliverables. Herein, we describe a marine halogenating enzyme-assisted bioconjugation strategy...

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Detalles Bibliográficos
Autores principales: Nguyen, Nguyet A., Agarwal, Vinayak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286304/
https://www.ncbi.nlm.nih.gov/pubmed/37272553
http://dx.doi.org/10.1021/acs.biochem.3c00222