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Progesterone attenuates Th17-cell pathogenicity in autoimmune uveitis via Id2/Pim1 axis

BACKGROUND: Autoimmune uveitis (AU) is the most common ophthalmic autoimmune disease (AD) and is characterized by a complex etiology, high morbidity, and high rate of blindness. AU remission has been observed in pregnant female patients. However, the effects of progesterone (PRG), a critical hormone...

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Detalles Bibliográficos
Autores principales: Liu, Xiuxing, Gu, Chenyang, Lv, Jianjie, Jiang, Qi, Ding, Wen, Huang, Zhaohao, Liu, Yidan, Su, Yuhan, Zhang, Chun, Xu, Zhuping, Wang, Xianggui, Su, Wenru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286326/
https://www.ncbi.nlm.nih.gov/pubmed/37344856
http://dx.doi.org/10.1186/s12974-023-02829-3