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Acrolein adducts and responding autoantibodies correlate with metabolic disturbance in Alzheimer’s disease

BACKGROUND: Alzheimer’s disease (AD) is caused by many intertwining pathologies involving metabolic aberrations. Patients with metabolic syndrome (MetS) generally show hyperglycemia and dyslipidemia, which can lead to the formation of aldehydic adducts such as acrolein on peptides in the brain and b...

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Detalles Bibliográficos
Autores principales: Sanotra, Monika Renuka, Kao, Shu-Huei, Lee, Ching-Kuo, Hsu, Chun-Hsien, Huang, Wen-Chung, Chang, Tsuei-Chuan, Tu, Fang-Yu, Hsu, I-Uen, Lin, Yung-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286356/
https://www.ncbi.nlm.nih.gov/pubmed/37349844
http://dx.doi.org/10.1186/s13195-023-01261-2