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Acrolein adducts and responding autoantibodies correlate with metabolic disturbance in Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is caused by many intertwining pathologies involving metabolic aberrations. Patients with metabolic syndrome (MetS) generally show hyperglycemia and dyslipidemia, which can lead to the formation of aldehydic adducts such as acrolein on peptides in the brain and b...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286356/ https://www.ncbi.nlm.nih.gov/pubmed/37349844 http://dx.doi.org/10.1186/s13195-023-01261-2 |