Perilipin5 protects against non-alcoholic steatohepatitis by increasing 11-Dodecenoic acid and inhibiting the occurrence of ferroptosis

BACKGROUND: Non-alcoholic steatohepatitis (NASH) is a major contributor to liver cirrhosis and hepatocellular carcinoma. There remains no effective pharmacological therapy. The hepatic lipid metabolism and fatty acid β-oxidation are regulated by Perilipin5 (Plin5). However, it is yet unknown how Pli...

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Detalles Bibliográficos
Autores principales: Xu, Xinming, Qiu, Jin, Li, Xiaoya, Chen, Juntong, Li, Yue, Huang, Xinmei, Zang, Shufei, Ma, Xinran, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286369/
https://www.ncbi.nlm.nih.gov/pubmed/37349836
http://dx.doi.org/10.1186/s12986-023-00751-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286369/
https://www.ncbi.nlm.nih.gov/pubmed/37349836
http://dx.doi.org/10.1186/s12986-023-00751-2

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