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Downregulated DUXAP8 lncRNA impedes trophoblast cell proliferation and migration by epigenetically upregulating TFPI2 expression

BACKGROUND: Preeclampsia (PE), a pregnancy complication characterized by new-onset hypertension and proteinuria during the second trimester, is the leading cause of neonatal and maternal morbidity and mortality. In the etiology of PE, failure of uterine spiral artery remodeling may be related to fun...

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Detalles Bibliográficos
Autores principales: Tang, Xiaotong, Cao, Yueying, Wu, Dan, Sun, Lizhou, Xu, Yetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286381/
https://www.ncbi.nlm.nih.gov/pubmed/37349838
http://dx.doi.org/10.1186/s12958-023-01108-3