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The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1

BACKGROUND: Transcription factor FOXM1 is a potential target for anti-cancer drug development. An interfering peptide M1-21, targeting FOXM1 and FOXM1-interacting proteins, is developed and its anti-cancer efficacy is evaluated. METHODS: FOXM1 C-terminus-binding peptides are screened by in silico pr...

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Detalles Bibliográficos
Autores principales: Cheng, Haojie, Yuan, Jie, Pei, Chaozhu, Ouyang, Min, Bu, Huitong, Chen, Yan, Huang, Xiaoqin, Zhang, Zhenwang, Yu, Li, Tan, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286459/
https://www.ncbi.nlm.nih.gov/pubmed/37344857
http://dx.doi.org/10.1186/s13578-023-01059-7