RHAMM regulates MMTV-PyMT-induced lung metastasis by connecting STING-dependent DNA damage sensing to interferon/STAT1 pro-apoptosis signaling

BACKGROUND: RHAMM is a multifunctional protein that is upregulated in breast tumors, and the presence of strongly RHAMM(+ve) cancer cell subsets associates with elevated risk of peripheral metastasis. Experimentally, RHAMM impacts cell cycle progression and cell migration. However, the RHAMM functio...

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Detalles Bibliográficos
Autores principales: Tolg, Cornelia, Milojevic, Maja, Qi, Freda W., Pavanel, Hailie A., Locke, M. Elizabeth O., Ma, Jenny, Price, Mathew, Nelson, Andrew C., McCarthy, James B., Hill, Kathleen A., Turley, Eva A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286489/
https://www.ncbi.nlm.nih.gov/pubmed/37349798
http://dx.doi.org/10.1186/s13058-023-01652-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286489/
https://www.ncbi.nlm.nih.gov/pubmed/37349798
http://dx.doi.org/10.1186/s13058-023-01652-1

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