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A Novel Shigella O-Polysaccharide–IpaB Conjugate Vaccine Elicits Robust Antibody Responses and Confers Protection against Multiple Shigella Serotypes

Shigella is responsible for high burdens of diarrhea and dysentery globally. Children living in areas of endemicity are the most affected, and currently, there are no licensed vaccines to prevent shigellosis. Vaccine approaches have traditionally targeted the bacterial lipopolysaccharide as a protec...

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Detalles Bibliográficos
Autores principales: Desalegn, Girmay, Kapoor, Neeraj, Pill-Pepe, Lucy, Bautista, Leslie, Yin, Lu, Ndungo, Esther, Oaks, Edwin V., Fairman, Jeff, Pasetti, Marcela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286710/
https://www.ncbi.nlm.nih.gov/pubmed/37017547
http://dx.doi.org/10.1128/msphere.00019-23