Cargando…

Linagliptin ameliorated cardiac fibrosis and restored cardiomyocyte structure in diabetic mice associated with the suppression of necroptosis

AIMS/INTRODUCTION: Linagliptin is a selective dipeptidyl peptidase (DPP)‐4 inhibitor capable of successfully regulating blood glucose levels. The cardiovascular protective effects of several DPP‐4 inhibitors have been shown in preclinical studies; however, the detailed influence of DPP‐4 inhibitors...

Descripción completa

Detalles Bibliográficos
Autores principales: Adhikari, Juthi, Hirai, Taro, Kawakita, Emi, Iwai, Kunimitsu, Koya, Daisuke, Kanasaki, Keizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286787/
https://www.ncbi.nlm.nih.gov/pubmed/37092329
http://dx.doi.org/10.1111/jdi.14017