Characterization of the biochemical activity and tumor-promoting role of the dual protein methyltransferase METL-13/METTL13 in Caenorhabditis elegans

The methyltransferase-like protein 13 (METTL13) methylates the eukaryotic elongation factor 1 alpha (eEF1A) on two locations: the N-terminal amino group and lysine 55. The absence of this methylation leads to reduced protein synthesis and cell proliferation in human cancer cells. Previous studies sh...

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Detalles Bibliográficos
Autores principales: Engelfriet, Melanie L., Małecki, Jędrzej M., Forsberg, Anna F., Falnes, Pål Ø., Ciosk, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286969/
https://www.ncbi.nlm.nih.gov/pubmed/37347777
http://dx.doi.org/10.1371/journal.pone.0287558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286969/
https://www.ncbi.nlm.nih.gov/pubmed/37347777
http://dx.doi.org/10.1371/journal.pone.0287558

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