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Mechanism of agonist-induced activation of the human itch receptor MRGPRX1

Mas-related G-protein-coupled receptors X1-X4 (MRGPRX1-X4) are 4 primate-specific receptors that are recently reported to be responsible for many biological processes, including itch sensation, pain transmission, and inflammatory reactions. MRGPRX1 is the first identified human MRGPR, and its expres...

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Detalles Bibliográficos
Autores principales: Gan, Bing, Yu, Leiye, Yang, Haifeng, Jiao, Haizhan, Pang, Bin, Chen, Yian, Wang, Chen, Lv, Rui, Hu, Hongli, Cao, Zhijian, Ren, Ruobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286997/
https://www.ncbi.nlm.nih.gov/pubmed/37347749
http://dx.doi.org/10.1371/journal.pbio.3001975