Increased plasma level of terminal complement complex in AMD patients: potential functional consequences for RPE cells

PURPOSE: Polymorphisms in complement genes are risk-associated for age-related macular degeneration (AMD). Functional analysis revealed a common deficiency to control the alternative complement pathway by risk-associated gene polymorphisms. Thus, we investigated the levels of terminal complement com...

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Detalles Bibliográficos
Autores principales: Busch, Catharina, Rau, Saskia, Sekulic, Andjela, Perie, Luce, Huber, Christian, Gehrke, Miranda, Joussen, Antonia M., Zipfel, Peter F., Wildner, Gerhild, Skerka, Christine, Strauß, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287163/
https://www.ncbi.nlm.nih.gov/pubmed/37359546
http://dx.doi.org/10.3389/fimmu.2023.1200725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287163/
https://www.ncbi.nlm.nih.gov/pubmed/37359546
http://dx.doi.org/10.3389/fimmu.2023.1200725

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