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The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory cytokine, protecting the body from an uncontrolled immune response, mostly through the Jak1/Tyk2 and STAT3 signaling...

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Detalles Bibliográficos
Autores principales: Carlini, Valentina, Noonan, Douglas M., Abdalalem, Eslam, Goletti, Delia, Sansone, Clementina, Calabrone, Luana, Albini, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287165/
https://www.ncbi.nlm.nih.gov/pubmed/37359549
http://dx.doi.org/10.3389/fimmu.2023.1161067