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Cathepsin inhibitors nitroxoline and its derivatives inhibit SARS-CoV-2 infection

The severity of the SARS-CoV-2 pandemic and the recurring (re)emergence of viruses prompted the development of new therapeutic approaches that target viral and host factors crucial for viral infection. Among them, host peptidases cathepsins B and L have been described as essential enzymes during SAR...

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Detalles Bibliográficos
Autores principales: Milan Bonotto, Rafaela, Mitrović, Ana, Sosič, Izidor, Martínez-Orellana, Pamela, Dattola, Federica, Gobec, Stanislav, Kos, Janko, Marcello, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287183/
https://www.ncbi.nlm.nih.gov/pubmed/37355023
http://dx.doi.org/10.1016/j.antiviral.2023.105655