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Depletion of abundant plasma proteins for extracellular vesicle proteome characterization: benefits and pitfalls

Blood extracellular vesicles (EVs) play essential roles in cell–cell communication and their molecular cargo is a promising source of disease biomarkers. However, proteomic characterization of plasma-derived EVs is challenged by the presence of highly abundant plasma proteins, which limits the detec...

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Detalles Bibliográficos
Autores principales: Reymond, Sandrine, Gruaz, Lyssia, Sanchez, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287573/
https://www.ncbi.nlm.nih.gov/pubmed/37069444
http://dx.doi.org/10.1007/s00216-023-04684-w