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Depletion of abundant plasma proteins for extracellular vesicle proteome characterization: benefits and pitfalls
Blood extracellular vesicles (EVs) play essential roles in cell–cell communication and their molecular cargo is a promising source of disease biomarkers. However, proteomic characterization of plasma-derived EVs is challenged by the presence of highly abundant plasma proteins, which limits the detec...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287573/ https://www.ncbi.nlm.nih.gov/pubmed/37069444 http://dx.doi.org/10.1007/s00216-023-04684-w |