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Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy

Antibodies with cross-reactive binding and broad toxin-neutralizing capabilities are advantageous for treating indications such as infectious diseases and animal envenomings. Such antibodies have been successfully selected against closely related antigens using phage display technology. However, the...

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Detalles Bibliográficos
Autores principales: Sørensen, Christoffer V., Ledsgaard, Line, Wildenauer, Helen H. K., Dahl, Camilla H., Ebersole, Tasja W., Bohn, Markus-Frederik, Ljungars, Anne, Jenkins, Timothy P., Laustsen, Andreas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287648/
https://www.ncbi.nlm.nih.gov/pubmed/37349546
http://dx.doi.org/10.1038/s41598-023-37056-6