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Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy
Antibodies with cross-reactive binding and broad toxin-neutralizing capabilities are advantageous for treating indications such as infectious diseases and animal envenomings. Such antibodies have been successfully selected against closely related antigens using phage display technology. However, the...
Autores principales: | Sørensen, Christoffer V., Ledsgaard, Line, Wildenauer, Helen H. K., Dahl, Camilla H., Ebersole, Tasja W., Bohn, Markus-Frederik, Ljungars, Anne, Jenkins, Timothy P., Laustsen, Andreas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287648/ https://www.ncbi.nlm.nih.gov/pubmed/37349546 http://dx.doi.org/10.1038/s41598-023-37056-6 |
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