Tetraspanin-8 sequesters syntaxin-2 to control biphasic release propensity of mucin granules

Agonist-mediated stimulated pathway of mucin and insulin release are biphasic in which rapid fusion of pre-docked granules is followed by slow docking and fusion of granules from the reserve pool. Here, based on a cell-culture system, we show that plasma membrane-located tetraspanin-8 sequesters syn...

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Detalles Bibliográficos
Autores principales: Wojnacki, José, Lujan, Agustin Leonardo, Brouwers, Nathalie, Aranda-Vallejo, Carla, Bigliani, Gonzalo, Rodriguez, Maria Pena, Foresti, Ombretta, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287693/
https://www.ncbi.nlm.nih.gov/pubmed/37349283
http://dx.doi.org/10.1038/s41467-023-39277-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287693/
https://www.ncbi.nlm.nih.gov/pubmed/37349283
http://dx.doi.org/10.1038/s41467-023-39277-9

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