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Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses

Licensed rabies virus vaccines based on whole inactivated virus are effective in humans. However, there is a lack of detailed investigations of the elicited immune response, and whether responses can be improved using novel vaccine platforms. Here we show that two doses of a lipid nanoparticle-formu...

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Detalles Bibliográficos
Autores principales: Hellgren, Fredrika, Cagigi, Alberto, Arcoverde Cerveira, Rodrigo, Ols, Sebastian, Kern, Theresa, Lin, Ang, Eriksson, Bengt, Dodds, Michael G., Jasny, Edith, Schwendt, Kim, Freuling, Conrad, Müller, Thomas, Corcoran, Martin, Karlsson Hedestam, Gunilla B., Petsch, Benjamin, Loré, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287699/
https://www.ncbi.nlm.nih.gov/pubmed/37349310
http://dx.doi.org/10.1038/s41467-023-39421-5