Structural basis of the interaction between BCL9-Pygo and LDB-SSBP complexes in assembling the Wnt enhanceosome

The Wnt enhanceosome is responsible for transactivation of Wnt-responsive genes and a promising therapeutic target for treatment of numerous cancers with Adenomatous Polyposis Coli (APC) or β-catenin mutations. How the Wnt enhanceosome is assembled remains poorly understood. Here we show that B-cell...

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Detalles Bibliográficos
Autores principales: Wang, Hongyang, Bienz, Mariann, Yan, Xiao-Xue, Xu, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287724/
https://www.ncbi.nlm.nih.gov/pubmed/37349336
http://dx.doi.org/10.1038/s41467-023-39439-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287724/
https://www.ncbi.nlm.nih.gov/pubmed/37349336
http://dx.doi.org/10.1038/s41467-023-39439-9

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