Galectin-3 activates spinal microglia to induce inflammatory nociception in wild type but not in mice modelling Alzheimer’s disease

Musculoskeletal chronic pain is prevalent in individuals with Alzheimer’s disease (AD); however, it remains largely untreated in these patients, raising the possibility that pain mechanisms are perturbed. Here, we utilise the TASTPM transgenic mouse model of AD with the K/BxN serum transfer model of...

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Detalles Bibliográficos
Autores principales: Sideris-Lampretsas, George, Oggero, Silvia, Zeboudj, Lynda, Silva, Rita, Bajpai, Archana, Dharmalingam, Gopuraja, Collier, David A., Malcangio, Marzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287730/
https://www.ncbi.nlm.nih.gov/pubmed/37349313
http://dx.doi.org/10.1038/s41467-023-39077-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287730/
https://www.ncbi.nlm.nih.gov/pubmed/37349313
http://dx.doi.org/10.1038/s41467-023-39077-1

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