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Galectin-3 activates spinal microglia to induce inflammatory nociception in wild type but not in mice modelling Alzheimer’s disease
Musculoskeletal chronic pain is prevalent in individuals with Alzheimer’s disease (AD); however, it remains largely untreated in these patients, raising the possibility that pain mechanisms are perturbed. Here, we utilise the TASTPM transgenic mouse model of AD with the K/BxN serum transfer model of...
Autores principales: | Sideris-Lampretsas, George, Oggero, Silvia, Zeboudj, Lynda, Silva, Rita, Bajpai, Archana, Dharmalingam, Gopuraja, Collier, David A., Malcangio, Marzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287730/ https://www.ncbi.nlm.nih.gov/pubmed/37349313 http://dx.doi.org/10.1038/s41467-023-39077-1 |
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