Mitochondrial aconitase suppresses immunity by modulating oxaloacetate and the mitochondrial unfolded protein response

Accumulating evidence indicates that mitochondria play crucial roles in immunity. However, the role of the mitochondrial Krebs cycle in immunity remains largely unknown, in particular at the organism level. Here we show that mitochondrial aconitase, ACO-2, a Krebs cycle enzyme that catalyzes the con...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Eunah, Annibal, Andrea, Lee, Yujin, Park, Hae-Eun H., Ham, Seokjin, Jeong, Dae-Eun, Kim, Younghun, Park, Sangsoon, Kwon, Sujeong, Jung, Yoonji, Park, JiSoo, Kim, Sieun S., Antebi, Adam, Lee, Seung-Jae V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287738/
https://www.ncbi.nlm.nih.gov/pubmed/37349299
http://dx.doi.org/10.1038/s41467-023-39393-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287738/
https://www.ncbi.nlm.nih.gov/pubmed/37349299
http://dx.doi.org/10.1038/s41467-023-39393-6

Ejemplares similares