Multiplexed ddPCR-amplicon sequencing reveals isolated Plasmodium falciparum populations amenable to local elimination in Zanzibar, Tanzania

Zanzibar has made significant progress toward malaria elimination, but recent stagnation requires novel approaches. We developed a highly multiplexed droplet digital PCR (ddPCR)-based amplicon sequencing method targeting 35 microhaplotypes and drug-resistance loci, and successfully sequenced 290 sam...

Descripción completa

Detalles Bibliográficos
Autores principales: Holzschuh, Aurel, Lerch, Anita, Gerlovina, Inna, Fakih, Bakar S., Al-mafazy, Abdul-wahid H., Reaves, Erik J., Ali, Abdullah, Abbas, Faiza, Ali, Mohamed Haji, Ali, Mohamed Ali, Hetzel, Manuel W., Yukich, Joshua, Koepfli, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287761/
https://www.ncbi.nlm.nih.gov/pubmed/37349311
http://dx.doi.org/10.1038/s41467-023-39417-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287761/
https://www.ncbi.nlm.nih.gov/pubmed/37349311
http://dx.doi.org/10.1038/s41467-023-39417-1

Ejemplares similares