Protein overproduction alters exosome secretion in Chinese hamster ovary cells

Despite the abundance of available cell lines, nearly 70% of all recombinant therapeutic proteins today are produced in Chinese hamster ovary (CHO) cells. The impact of protein overproduction on the secretion of exosomes by CHO cells has been investigated here. Increased secretion of extracellular v...

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Detalles Bibliográficos
Autores principales: Steć, Aleksandra, Targońska, Monika, Karkosińska, Edyta, Słowik, Monika, Płoska, Agata, Kalinowski, Leszek, Wielgomas, Bartosz, Waleron, Krzysztof, Jasiecki, Jacek, Dziomba, Szymon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Paper in Forefront
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287810/
https://www.ncbi.nlm.nih.gov/pubmed/37160422
http://dx.doi.org/10.1007/s00216-023-04725-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287810/
https://www.ncbi.nlm.nih.gov/pubmed/37160422
http://dx.doi.org/10.1007/s00216-023-04725-4

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