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Involvement of Ca(2+) in Signaling Mechanisms Mediating Muscarinic Inhibition of M Currents in Sympathetic Neurons
Acetylcholine can excite neurons by suppressing M-type (KCNQ) potassium channels. This effect is mediated by M(1) muscarinic receptors coupled to the G(q) protein. Although PIP(2) depletion and PKC activation have been strongly suggested to contribute to muscarinic inhibition of M currents (I(M)), d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287826/ https://www.ncbi.nlm.nih.gov/pubmed/36369494 http://dx.doi.org/10.1007/s10571-022-01303-7 |