Cargando…
Involvement of Ca(2+) in Signaling Mechanisms Mediating Muscarinic Inhibition of M Currents in Sympathetic Neurons
Acetylcholine can excite neurons by suppressing M-type (KCNQ) potassium channels. This effect is mediated by M(1) muscarinic receptors coupled to the G(q) protein. Although PIP(2) depletion and PKC activation have been strongly suggested to contribute to muscarinic inhibition of M currents (I(M)), d...
Autores principales: | Yoon, Jin-Young, Ho, Won-Kyung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287826/ https://www.ncbi.nlm.nih.gov/pubmed/36369494 http://dx.doi.org/10.1007/s10571-022-01303-7 |
Ejemplares similares
-
cPLA(2)α(-/-) sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca(2+) current inhibition by M(1) muscarinic receptor signaling
por: Liu, Liwang, et al.
Publicado: (2018) -
Heterogeneity of release-regulating muscarinic receptors in rat sympathetic neurons: evidence for inhibitory presynaptic M(1 )receptors
por: Kubista, Helmut, et al.
Publicado: (2008) -
Excitation of rat sympathetic neurons via M(1) muscarinic receptors independently of K(v)7 channels
por: Salzer, Isabella, et al.
Publicado: (2014) -
Protease-Activated Receptor 2 Activation Inhibits N-Type Ca(2+) Currents in Rat Peripheral Sympathetic Neurons
por: Kim, Young-Hwan, et al.
Publicado: (2014) -
NGF Inhibits M/KCNQ Currents and Selectively Alters Neuronal Excitability in Subsets of Sympathetic Neurons Depending on their M/KCNQ Current Background
por: Jia, Zhanfeng, et al.
Publicado: (2008)