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Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR

Classic promoter mutagenesis strategies can be used to study how proximal promoter regions regulate the expression of particular genes of interest. This is a laborious process, in which the smallest sub-region of the promoter still capable of recapitulating expression in an ectopic setting is first...

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Detalles Bibliográficos
Autores principales: FitzPatrick, Vincent D, Leemans, Christ, van Arensbergen, Joris, van Steensel, Bas, Bussemaker, Harmen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287907/
https://www.ncbi.nlm.nih.gov/pubmed/37013986
http://dx.doi.org/10.1093/nar/gkad232