MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1

DNA double-strand break (DSB) repair via homologous recombination is initiated by end resection. The extent of DNA end resection determines the choice of the DSB repair pathway. Nucleases for end resection have been extensively studied. However, it is still unclear how the potential DNA structures g...

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Detalles Bibliográficos
Autores principales: Oh, Jung-Min, Kang, Yujin, Park, Jumi, Sung, Yubin, Kim, Dayoung, Seo, Yuri, Lee, Eun A, Ra, Jae Sun, Amarsanaa, Enkhzul, Park, Young-Un, Lee, Seon Young, Hwang, Jung Me, Kim, Hongtae, Schärer, Orlando, Cho, Seung Woo, Lee, Changwook, Takata, Kei-ichi, Lee, Ja Yil, Myung, Kyungjae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287916/
https://www.ncbi.nlm.nih.gov/pubmed/37140056
http://dx.doi.org/10.1093/nar/gkad308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287916/
https://www.ncbi.nlm.nih.gov/pubmed/37140056
http://dx.doi.org/10.1093/nar/gkad308

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