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On the dependent recognition of some long zinc finger proteins

The human genome contains about 800 C2H2 zinc finger proteins (ZFPs), and most of them are composed of long arrays of zinc fingers. Standard ZFP recognition model asserts longer finger arrays should recognize longer DNA-binding sites. However, recent experimental efforts to identify in vivo ZFP bind...

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Detalles Bibliográficos
Autores principales: Zuo, Zheng, Billings, Timothy, Walker, Michael, Petkov, Petko M, Fordyce, Polly M, Stormo, Gary D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287918/
https://www.ncbi.nlm.nih.gov/pubmed/36951113
http://dx.doi.org/10.1093/nar/gkad207