Screening for functional regulatory variants in open chromatin using GenIE-ATAC

Understanding the effects of genetic variation in gene regulatory elements is crucial to interpreting genome function. This is particularly pertinent for the hundreds of thousands of disease-associated variants identified by GWAS, which frequently sit within gene regulatory elements but whose functi...

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Detalles Bibliográficos
Autores principales: Cooper, Sarah, Schwartzentruber, Jeremy, Coomber, Eve L, Wu, Qianxin, Bassett, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287956/
https://www.ncbi.nlm.nih.gov/pubmed/37125635
http://dx.doi.org/10.1093/nar/gkad332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287956/
https://www.ncbi.nlm.nih.gov/pubmed/37125635
http://dx.doi.org/10.1093/nar/gkad332

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