Allosteric Activation of Transglutaminase 2 via Inducing an “Open” Conformation for Osteoblast Differentiation

Osteoblasts play an important role in the regulation of bone homeostasis throughout life. Thus, the damage of osteoblasts can lead to serious skeletal diseases, highlighting the urgent need for novel pharmacological targets. This study introduces chemical genetics strategy by using small molecule fo...

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Detalles Bibliográficos
Autores principales: Yang, Zhuo, Zhang, Xiao‐Wen, Zhuo, Fang‐Fang, Liu, Ting‐Ting, Luo, Qian‐Wei, Zheng, Yong‐Zhe, Li, Ling, Yang, Heng, Zhang, Yi‐Chi, Wang, Yan‐Hang, Liu, Dan, Tu, Peng‐Fei, Zeng, Ke‐Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288273/
https://www.ncbi.nlm.nih.gov/pubmed/37088726
http://dx.doi.org/10.1002/advs.202206533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288273/
https://www.ncbi.nlm.nih.gov/pubmed/37088726
http://dx.doi.org/10.1002/advs.202206533

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