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The Combination of R848 with Sorafenib Enhances Antitumor Effects by Reprogramming the Tumor Immune Microenvironment and Facilitating Vascular Normalization in Hepatocellular Carcinoma

Novel promising strategies for combination with sorafenib are urgently needed to enhance its clinical benefit and overcome toxicity in hepatocellular carcinoma (HCC). the molecular and immunomodulatory antitumor effects of sorafenib alone and in combination with the new immunotherapeutic agent R848...

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Detalles Bibliográficos
Autores principales: He, Yuchao, Zhan, Linlin, Shi, Jian, Xiao, Manyu, Zuo, Ran, Wang, Chengmeng, Liu, Zhiyong, Gong, Wenchen, Chen, Liwei, Luo, Yi, Zhang, Shaojun, Wang, Youwei, Chen, Lu, Guo, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288281/
https://www.ncbi.nlm.nih.gov/pubmed/37083239
http://dx.doi.org/10.1002/advs.202207650