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Joint use of population pharmacokinetics and machine learning for optimizing antiepileptic treatment in pediatric population
PURPOSE: Unpredictable drug efficacy and safety of combined antiepileptic therapy is a major challenge during pharmacotherapy decisions in everyday clinical practice. The aim of this study was to describe the pharmacokinetics of valproic acid (VA), lamotrigine (LTG), and levetiracetam (LEV) in a ped...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288421/ https://www.ncbi.nlm.nih.gov/pubmed/37359445 http://dx.doi.org/10.1177/20420986231181337 |