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Joint use of population pharmacokinetics and machine learning for optimizing antiepileptic treatment in pediatric population

PURPOSE: Unpredictable drug efficacy and safety of combined antiepileptic therapy is a major challenge during pharmacotherapy decisions in everyday clinical practice. The aim of this study was to describe the pharmacokinetics of valproic acid (VA), lamotrigine (LTG), and levetiracetam (LEV) in a ped...

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Detalles Bibliográficos
Autores principales:	Damnjanović, Ivana, Tsyplakova, Nastia, Stefanović, Nikola, Tošić, Tatjana, Catić-Đorđević, Aleksandra, Karalis, Vangelis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288421/ https://www.ncbi.nlm.nih.gov/pubmed/37359445 http://dx.doi.org/10.1177/20420986231181337

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