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Bicyclic Engineered Sortase A Performs Transpeptidation under Denaturing Conditions
[Image: see text] Enzymes are of central importance to many biotechnological and biomedical applications. However, for many potential applications, the required conditions impede enzyme folding and therefore function. The enzyme Sortase A is a transpeptidase that is widely used to perform bioconjuga...
Autores principales: | Kiehstaller, Sebastian, Hutchins, George H., Amore, Alessia, Gerber, Alan, Ibrahim, Mohamed, Hennig, Sven, Neubacher, Saskia, Grossmann, Tom N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288436/ https://www.ncbi.nlm.nih.gov/pubmed/37246906 http://dx.doi.org/10.1021/acs.bioconjchem.3c00151 |
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