Cargando…

Design and Evolution of Enhanced Peptide–Peptide Ligation for Modular Transglutaminase Assembly

[Image: see text] Robust and precise tools are needed to enhance the functionality and resilience of synthetic nanoarchitectures. Here, we have employed directed evolution and rational design to build a fast-acting molecular superglue from a bacterial adhesion protein. We have generated the SnoopLig...

Descripción completa

Detalles Bibliográficos
Autores principales: Keeble, Anthony H., Wood, Dominic P., Howarth, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288437/
https://www.ncbi.nlm.nih.gov/pubmed/37289810
http://dx.doi.org/10.1021/acs.bioconjchem.3c00122