Pharmacokinetic interaction of voriconazole and clarithromycin in Pakistani healthy male volunteers: a single dose, randomized, crossover, open-label study

Background: Voriconazole an antifungal drug, has a potential for drug-drug interactions (DDIs) with administered drugs. Clarithromycin is a Cytochromes P450 CYP (3A4 and 2C19) enzyme inhibitor, and voriconazole is a substrate and inhibitor of these two enzymes. Being a substrate of the same enzyme f...

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Detalles Bibliográficos
Autores principales: Mushtaq, Mehwish, Fatima, Kshaf, Ahmad, Aneeqa, Mohamed Ibrahim, Osama, Faheem, Muhammad, Shah, Yasar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288581/
https://www.ncbi.nlm.nih.gov/pubmed/37361220
http://dx.doi.org/10.3389/fphar.2023.1134803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288581/
https://www.ncbi.nlm.nih.gov/pubmed/37361220
http://dx.doi.org/10.3389/fphar.2023.1134803

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