An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo

The classical manifestation of COVID-19 is pulmonary infection. After host cell entry via human angiotensin–converting enzyme II (hACE2), the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can infect pulmonary epithelial cells, especially the AT2 (alveolar type II) cells that are...

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Detalles Bibliográficos
Autores principales: Liu, Kuo, Tang, Muxue, Xu, Wei, Meng, Xinfeng, Jin, Hengwei, Han, Maoying, Pu, Jing, Li, Yutang, Jiao, Fanke, Sun, Ruilin, Shen, Ruling, Lui, Kathy O., Lu, Lu, Zhou, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288645/
https://www.ncbi.nlm.nih.gov/pubmed/37307455
http://dx.doi.org/10.1073/pnas.2207210120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288645/
https://www.ncbi.nlm.nih.gov/pubmed/37307455
http://dx.doi.org/10.1073/pnas.2207210120

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